Stroke and transient ischemic attack

In ischemic stroke antithrombotic treatment is started as soon as intracranial bleeding has been excluded with neuroimaging. For emergency treatment rt‐PA (Actilyse) should be considered if it can be started within 4.5 h from symptom onset and no contraindications are present. For antithrombotic pre...

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Published in: Essential Guide to Blood Coagulation pp. 121 - 124
Main Authors: Wahlgren, Nils, von Euler, Mia
Format: Book Chapter
Language: English
Published: Oxford, UK John Wiley & Sons Ltd 04-15-2013
Subjects:
TIA
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Summary: In ischemic stroke antithrombotic treatment is started as soon as intracranial bleeding has been excluded with neuroimaging. For emergency treatment rt‐PA (Actilyse) should be considered if it can be started within 4.5 h from symptom onset and no contraindications are present. For antithrombotic prevention, acetylsalicylic acid (ASA) 75‐100 mg daily (bolus dose first day of 300 mg) is recommended. For long‐term secondary prevention, ASA and dipyridamol 200 mg twice daily or monotherapy with clopidogrel 75 mg daily is recommended. If atrial fibrillation is present, anticoagulants are strongly recommended. For venous sinus thrombosis treatment with unfractionated heparin (UFH) and simultaneous initiation of VKA treatment is recommended, provided there are no contraindications.
ISBN: 9781118288795
1118288793
DOI: 10.1002/9781118327517.ch12